Betametason valerat

Betametason valerat
Nama sistematis (IUPAC)
	(11β,16β)-9-Fluoro-11,21-dihidroksi-16-metil-3,20-dioksopregna-1,4-dien-17-il valerat
Data klinis
Nama dagang	Benczema, Benoson, dll
AHFS/Drugs.com	monograph
Kat. kehamilan	?
Status hukum	?
Pengenal
Nomor CAS	2152-44-5
Kode ATC	?
PubChem	CID 16533
ChemSpider	15673
UNII	9IFA5XM7R2
ChEBI	CHEBI:31277
ChEMBL	CHEMBL1497
Sinonim	Betametason 17-valerat
Data kimia
Rumus	C27H37FO6
	InChI InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1 ; Key:SNHRLVCMMWUAJD-SUYDQAKGSA-N ;

Betametason valerat adalah ester glukokortikoid sintetis. Ini adalah ester 17-valerat dari betametason.^[1]^[2] Betametason valerat sering digunakan untuk mengobati eksim ringan dengan kemanjuran yang baik dan insiden efek samping yang disebabkan steroid yang lebih rendah karena potensinya yang lebih rendah dibandingkan dengan glukokortikoid lainnya. Betametason-17-valerat tersedia dalam bentuk krim, salep, losion, dan sediaan busa untuk penggunaan topikal.^[3]^[4]^[5]

Referensi

^ Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.
^ "Betamethasole valerate". PubChem. U.S. National Library of Medicine.
^ Raveendran R (November 2019). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America. 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. PMID 31563186. S2CID 202816063.
^ Payne J, Habet KA, Pona A, Feldman SR (August 2019). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. PMID 31424707.
^ Duweb GA, Abuzariba O, Rahim M, al-Taweel M, Abdulla SA (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. PMID 11314240.

[1] Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.

[2] "Betamethasole valerate". PubChem. U.S. National Library of Medicine.

[:0-3] Raveendran R (November 2019). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America. 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. PMID 31563186. S2CID 202816063.

[4] Payne J, Habet KA, Pona A, Feldman SR (August 2019). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. PMID 31424707.

[5] Duweb GA, Abuzariba O, Rahim M, al-Taweel M, Abdulla SA (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. PMID 11314240.

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